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Developed in collaboration with Mitchell Holland, Ph.D., Associate Director of The Pennsylvania State University's Forensic Science Program. Review Dr. Holland's GeneMarkerHID Poster. Reduce analysis time by up to 25% with GeneMarkerHID! GeneMarker® HID is an excellent choice for forensic genotyping applications. This software can be employed as a "biologist friendly" replacement for GeneScan®/GenoTyper® or as an alternative to GeneMapper® ID. GeneMarker® HID uses advanced Windows technology that is intuitive and easy to learn. In addition to standard STR analysis, GeneMarker HID has been optimized to analyze profiles from Y-STRs, LCN samples, ABI's MiniFilerTM Kit, and Locus Specific Bracket (LSB) data. These new applications are revolutionizing the DNA forensic community! Reduce casework backlog with these key software features:
Advantages of GeneMarker HID are ease of use and accurate, quick analysis. GeneMarker HID utilizes unique sizing algorithms and pattern recognition technology to provide unparalleled accuracy up to 99%. The majority of functions have been completely automated, using a “smart” software approach to eliminate the need for constant analyst intervention, and to improve analysis to analysis consistency.
Rapid Data Processing, Instrument Correction and Compatibility GeneMarker HID can perform STR analysis on over 1,000 lanes of data using
the following ABI
The software accepts data format out put by ABI PRISM® 310/3100/3130 Genetic Analyzer instruments, as well as MegaBACE and Beckman CE systems. GeneMarker HID automatically adjusts for — instrument spike, color pull-up, peak pull-up, noisy data, saturated peaks, and stutter peaks—saving significant analysis time and cost, efficiently analyzing raw STR data within seconds. In addition, GeneMarker HID allows the user to conduct a lane by lane overview of unprocessed raw data, permitting a quick quality control assessment of your profiles.
Three Simple Clicks to Analysis
Setting analysis parameters is accomplished through 3 easy-to-use dialogue boxes. Once parameters have been set, they can be saved for future analysis, allowing “single click” operation of the AutoRun feature.
A few notable features of GeneMarker HID’s analysis window include automatic RFU intensity ranging in the electropherogram (see example above), distinct peak flags, and several customizable viewing modes. In addition to a user friendly interface, GeneMarker HID also provides an enhanced quality scoring system (see example below) that flags suspect alleles and identifies samples that have questionable size calling results.
Customizable
Panels and Size Standards
Paternity Testing and Missing Persons ID GeneMarker HID includes an imbedded Pedigree Tool for family tree analysis.
This function allows the user to easily add mates and offspring and it
automatically identifies allele conflicts between parents and/or siblings.
Create an original pedigree file from new data or import pre-made pedigree
files (.pre, .ped, .smp). Future applications of the Pedigree Tool include
relationship testing and databasing of family samples. See our Relationship
Testing poster from the 2007 International Symposium on Human Identification. Pedigree
Analysis
Select to previously analyzed projects and compare the results with GeneMarker HID's unique Project Comparison Tool. The Project Comparison Tool aligns two projects and identifies differences in peak size, height, and allele call. Additionally, if an analyst edited an allele call, the results can be immediately corroborated. The Project Comparison Tool can also be used during validation to examine the affects of certain analysis parameters on allele calling. Rapid Analysis Review
Numerous Printing & Reporting Options Nearly every function of GeneMarker HID has been automated so that once the template is selected from the menu, or created by the user, the software automatically performs the initial data analysis in preparation for user review, thereby providing a myriad of display and reporting options. Analysis results can be sorted and manipulated to meet report requirements and then saved as a text file for input into LIMS or other data base systems. CODIS files can be easily generated and exported. In addition, GeneMarker HID will print electropherograms and peak tables in bulk for either all or selected sample sets in a logical, easy to read format.
If you would like to download the GeneMarker® HID brochure please click here. (Adobe PDF 630kb) Registered Trademarks are the property of their respective owners.
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Copyright © 2008