User Management and Validation Tools for DNA Fragment Analysis in
GeneMarker® Genotyping Software
GeneMarker software is a biologist-friendly genotyping program with additional tools to assist researchers with DNA fragment analysis. The program is compatible with all capillary electrophoresis instruments (ABI®PRISM, Beckman-Coulter®, MegaBACE®) and is a powerful alternative to GeneMapper®, Genotyper™, GeneScan®, CEQ™ Fragment Analysis Software. In addition to accurate size calling algorithm options and a flexible panel editor, GeneMarker software includes User Management and Project Comparison Tools. User management provides control of user access rights, automatically generates an audit trail of all edits to genotyping projects and is used to customize the Organization and Operator fields in final print reports such as MLPA, MS-MLPA, Trisomy, Cystic Fibrosis, LOH and MSI . The Project Comparison Tool provides researchers with a linked comparison of two replicate projects. It is an excellent validation tool for instrumentation, analysis parameters or chemistries; providing a peak by peak comparison and identifying any differences between the project results. Uses include establishing and comparing analysis parameters, validation studies for instrumentation or chemistries, and ensuring consistent calls of edited alleles (especially beneficial for long term projects to confirm that edits/comments are consistently applied).
User Management for Audit Trail, Electronic Signature/Verification of Analyst and Control of User Access Rights in GeneMarker Genotyping Software
User management provides control of user access rights, automatically generates an audit trail of all edits to genotyping projects and is used to record the Organization and Operator fields in the clinical research print reports (MLPA®, Trisomy, LOH, MSI
Records the computer's date and time for the activity.
Identifies the username of the person that performed the activity.
Records the user manager activity that was performed.
Gives additional information for the event that was performed. For example, if a user is added, then the username of the person that was added is recorded under Comments.
Example of Clinical Research Report Customization with Institution and Analyst Identification
supplied from the User Management Tool in GeneMarker.
Trademarks property of their respective owners
MLPA® (Multiplex Ligation‐dependent Probe Amplification)
Macromolecule Analysis Tool
ARMs & Comparative Analysis (Cystic Fibrosis Analysis)
MSI (Microsatellite Instability) Analysis
Kinship Analysis of Wild Populations and data base
Microsatellite (SSR, STR, VNTR)
TILLING® & EcoTilling with slabgel or capillary data
Loss of Heterozygosity Analysis (LOH)